Product Description
The last two decades have witnessed a phenomenal growth in the field of genetic or biochemical engineering, and a variety of products has been developed and marketed through the manipulation and growth of different types of microorganisms and the recovery and purification of the associated products.

Handbook of Downstream Processing

Product Description
Looks at developments in the life sciences, explaining cells, chromosomes, viruses and bacteria. The book postulates a new theory about the origins of behaviour: that human nature lies in the cells. It also examines cloning and future genetic research.Amazon.com Review
“Pasteur,” Brian Ford believes, “did us all a great disservice.” His germ theory of disease bequeathed to us a fear of microbes, and consequently an aversion to unicellular life. This aversion is only heightened by those biologists for whom the cell is merely a dumb vehicle for selfish DNA.

In a book whose title badly belies its true subject, cells themselves are, Ford says, “living entities with minds of their own”; not a mere information packet, the living cell is revealed as the fundamental, pluripotent agent of life on earth. “I want to show that we can understand ourselves only as manifestations of the cells of which we are composed,” Ford writes. “Everything we do is a reflection of the separate cells whose choreographed interactions make us what we are.”

Ford’s fascinating account ranges from the (occasionally literally) explosive biochemistry of human life to the myriad microbial populations vital to our well-being. Ford strips modern genetics of its fearsome millennialist mask. Genetics has a long history–even a prehistory–and the changes ushered in through modern techniques, while they should not be minimized or ignored, are only a tiny part of the whole story.

Ford’s concluding speculations, applying the lessons of cellular behavior to individuals and even human societies, open up exciting possibilities for further research while treating the casual reader to an engaging, distinctly acerbic account of human nature. –Simon Ings, Amazon.co.uk

Genes: The Fight for Life

Product Description
Translated by Charles Wilkinson. This Elibron Classics book is a facsimile reprint of a 1807 edition published in London.

A General, Historical, and Topographical Description of Mount Caucasus. With a Catalogue of Plants Indigenous to the Country: Volume 2

Product Description
A timely overview of this rapidly-expanding topic, covering the most important classes of compounds and incorporating the latest literature. With its application-oriented approach, this book is the first to emphasize current and potential applications, extending to such fields as materials science, bioorganic chemistry, medicinal chemistry, and organic synthesis. In the biological context in particular, the book clarifies which receptor systems work well in water or better under physiological conditions.

From the contents:

• Amino Acid, Peptid and Protein Receptors
• Carbohydrate Receptors
• Ammonium, Amidinium and Guanidinium Receptors
• Anion Receptors
• Molecular Capsules and Self Assembly
• Dynamic Combinatorial Libraries based on Molecular Recognition
• Molecular Machines
• Self-Replication

Aimed at graduate students and specialists in the field, this is also of interest to pharmaceutical companies involved in drug design, as well as chemical companies with a polymer or nanotechnology group. In addition, analytical companies working on the advanced equipment covered here will find stimulating new applications.

Functional Synthetic Receptors

Product Description

The BIFI2006 Conference represents an interactive forum for physicists, chemists, biologists, and mathematicians for sharing ideas as well as addressing recent advances in the frontier between physics and biology. There were three main topics at the conference: nucleic acids, proteins and peptides, and collective behavior of biomolecules. This volume includes papers on: protein folding, nucleic acid structure, ligand binding and proteomics.

From Physics to Biology: The Interface between Experiment and Computation: Bifi 2006 II International Congress

Product Description
Amyloids, Prions and Beta Proteins is the last volume of the three-part thematic series on Fibrous Proteins in the Advances in Protein Chemistry serial. Fibrous proteins act as molecular scaffolds in cells providing the supporting structures of our skeletons, bones, tendons, cartilage, and skin. They define the mechanical properties of our internal hollow organs such as the intestines, heart, and blood vessels. This volume covers such topics as Beta-Structures in Fibrous Proteins; B-Silks: Enhancing and Controlling Aggregation; Beta-Rolls, Beta-Helices and Other Beta-Solenoid Proteins; Natural Triple B-Stranded Fibrous Folds; Structure, Function and Amyloidogenesis of Fungal Prions: Filament Polymorphism and Prion Variants; X-Ray Fiber and powder Diffraction of PRP Prion Peptides; From the Polymorphism of Amyloid Fibrils to Their Assembly Mechanism and Cytotoxicity; Structural Models of Amyloid-like Fibrils.

Fibrous Proteins: Amyloids, Prions and Beta Proteins, Volume 73

Product Description
Extra- and Intracellular Calcium and Phosphate Regulation: From Basic Research to Clinical Medicine presents thinking and front-line research addressing calcium and phosphate homeostasis and related clinical problems. Major topics include calcium and phosphate transport in the mammalian body and some of its defects; several aspects of hormonal control of calcium and phosphorus metabolism, including PTH-related peptide; and basic and clinical aspects of bone and bone diseases. Other topics include calcium entry and extrusion mechanisms, secondary osteoporosis, how bone cells translocate phosphate needed to bone mineral, and the culture of renal and intestinal cells capable of transporting calcium in vitro. The book also features two prize-winning contributions; one deals with the characterization of a major calcium transport protein, calbindin D-9K, while the other discusses how the osteoclast, the bone-resorbing cell, is feedback-regulated.Extra- and Intracellular Calcium and Phosphate Regulation: From Basic Research to Clinical Medicine provides plenty of useful information for basic and clinical scientists alike, including biochemists, physiologists, cell biologists, pharmacologists, internists, orthopedic surgeons, dentists, and pathologists.

Extra- and Intracellular Calcium and Phosphate Regulation: From Basic Research to Clinical Medicine

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The Encyclopedic Reference provides a broad overview of the topics and issues which are central to an understanding of molecular biology and molecular medicine, in addition to up-to-the minute information about developments in the field including pharmocogenics and pharmacoproteomics, gene therapy and gene regulation. Particular emphasis is placed on the molecular causes of disease.

Presented in an A-Z format, the Encyclopedia contains over 2000 entries written by leading experts in genomics and proteomics. Entries comprise in-depth essays, illustrated with full-colour figures, and short entry keywords, which provide an opportunity for non-specialists to gain a more complete understanding of each topic through the explanation of specialist terminology. The book is accompanied by a CD-ROM, which provides the full text and facilitated searches. The Encyclopedic Reference will be of value to clinical scientists in academia as well as industry, in addition to people working in related fields, students, teachers, and interested laypeople.

Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine

Product Description
Barrier, reservoir, target site – those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore the prerequisite for a better understanding of drug action. Many of today’s pharmaceuticals are amphiphilic or catamphiphilic, enabling them to interact with biological membranes.
Crucial membrane properties are surveyed and techniques to elucidate drug-membrane interactions presented, including computer-aided predictions. Effects of membrane interaction on drug action and drug distribution are discussed, and numerous examples are given.
This unique reference volume builds on the authors’ long experience in the study of drug-membrane interaction. Recommended reading for everyone involved in pharmaceutical research.

Drug-Membrane Interactions: Analysis, Drug Distribution, Modeling

Product Description

The Workshop combined different fields of molecular nanotechnology applying DNA either as subject of studies or as a molecular building block. As the first meeting solely focusing on DNA-nanotechnology, the heterogeneous scientific background of the participants in physics, chemistry, and biology provided a comprehensive account of the state-of-the-art in this multidisciplinary field and previewed the trends for further research in this promising field.

DNA-Based Molecular Construction: International Workshop on DNA-based Molecular Construction, Jena, Germany, 23-25 May 2002