Product Description
Obesity has become the most common chronic disease of the present day, with significant increases in prevalence in populations across the world and all age groups. This has resulted in a dramatic increase in obesity-related metabolic and cardiovascular complications, making it an important public health issue.

Type 2 diabetes associated with obesity or ‘diabesity’ is today the most common form of type 2 diabetes. It is also associated with a number of other cardiovascular risk factors, which constitute the metabolic syndrome. Effective management of ‘diabesity’ is crucial to the reduction of morbidity and premature mortality due to cardiovascular disease.

This book comprises chapters written by leading international experts on various aspects of obesity-related diabetes. As a practical reference guide, it is suitable for all professionals with an interest in this field. Emerging problems such as childhood ‘diabesity’ and the impact of obesity on polycystic ovary syndrome will be of interest not only to paediatricians and endocrinologists, but also to general practitioners and other healthcare professionals.

The contemporary approach to the clinical assessment of obesity and its management in both primary and secondary care settings is also described.

Obesity and Diabetes

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Product Description
Diabetes research on models comprising intact animal tissues, cell cultures and isolated pancreatic islets is essential for understanding the pathogenesis of the disease as well as the mechanisms responsible for the chronic complications associated with it. Enormous advances in the understanding of the development of diabetes and its prevention have recently been derived from work with such animal models. This book presents the state-of-the-art knowledge in the field of diabetes research directed at understanding the mechanisms governing the development of skeletal muscle insulin resistance. Muscle Metabolism will be of significant interest for those researching diabetes at an experimental level in both academia and the pharmaceutical industry. In addition, it will also be of interest to researchers in the fields of obesity, metabolism, endocrinology and molecular biology.

Muscle Metabolism

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• Explains Metabolic Syndrome, a constellation of factors including obesity,high glucose levels in the blood, high blood pressure and abnormal cholesterol levels.
• Illustrates and explains each of the risk factors in detail.
• Also lists causes, treatments and the medical conditions associated with this disease, which affects about 1 in 4 Americans.
• Size is 20 inches by 26 inches – Flexible plastic 1.5 mil lamination – Anatomical Chart.

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Metabolic Syndrome Anatomical Chart

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• Explains Metabolic Syndrome, a constellation of factors including obesity,high glucose levels in the blood, high blood pressure and abnormal cholesterol levels.
• Illustrates and explains each of the risk factors in detail.
• Also lists causes, treatments and the medical conditions associated with this disease, which affects about 1 in 4 Americans.
• Size is 20 inches by 26 inches – Flexible plastic 1.5 mil lamination – Anatomical Chart.

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Metabolic Syndrome Anatomical Chart

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Product Description
Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book the authors draw upon 50 years of multidisciplinary clinical and investigative follow-up of the large Israeli cohort of LS patients. The genetic basis of the syndrome is fully considered, and all aspects of the pathophysiology of IGF-I deficiency are described. Data derived from the recently generated mouse model of LS are reviewed and compared with the human LS experience. Valuable advice is provided on treatment, and treatment effects, such as metabolic effects, adipose tissue alterations, and impact on aging, are fully explored. Together, this book condenses, consolidates, compares, and contrasts data derived from the human and mouse LS experiences and provides a unique resource for clinical and basic scientists to evaluate and compare IGF-I and GH actions.

Laron Syndrome – From Man to Mouse: Lessons from Clinical and Experimental Experience

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Product Description
This provides a scholarly synthesis of the current knowledge of the vertebrate growth process and how it is controlled by hormones and growth factors. Like the other volumes of the Handbook of Physiology Series this text focuses on the considerable body of work that has emerged in the last 25 years. The book begins with an overview of the growth process and how it is assessed in the laboratory and the clinic, as well as the roles played by the various hormones in the growth of nonmammalian vertebrates, domestic animals and humans. A major section on the central role of growth hormone in the regulation of somatic growth follows, including chapters on structure-function relationships, gene expression, regulation of secretion, receptors, cell-signalling mechanisms, and their mechanisms of action related to somatic growth. The last section covers the cellular and molecular mechanisms of action of the thryoid gland and insulin on growth. This volume is valuable source for the student, teacher or researcher of the most up-to-date knowledge of how hormones regulate growth in vertebrate animals and humans.

Handbook of Physiology: Section 7: The Endocrine System Volume V: Hormonal Control of Growth

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Handbook of Diabetic Hypertension incorporates the latest guidelines and trials into a practical, concise, authoritative guide to the diagnosis, evaluation, and management of hypertension in type 2 diabetes, the most prevalent form of the disease. Adjunctive measures to lower cardiac risk and improve cardiovascular prognosis are also described, including intensive control of glycemia and diabetic dyslipidemia.

Handbook of Diabetic Hypertension 2006

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…a handy reference written specifically for clinical chemists, chemical pathologists, endocrinologists, & medical technologists to aid in the investigation of endocrine and metabolic disorders…addresses common and rare disorders.

Handbook of Diagnostic Endocrinology

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Product Description
This issue of Endocrinology and Metabolism Clinics of North America aims to become the first compilation of interest to both the Endocrinologist and Critical Care specialist by compiling the latest findings into one volume. Split in to two major areas, this volume covers life-threatening illnesses caused by primary endocrine diseases and examines endocrinology from the ICU perspective.

First section deals with classic life-threatening illnesses, such as: thyrotoxicosis, hypothyroidism, pheochromocytoma, severe hyper- end hypoglycemia, acute adrenal crises.

Second section goes in to more in-depth coverage of these endocrine diseases from the needs of the ICU, starting with a general overview of the dynamic neuroendocrine and metabolic stress responses in the condition of intensive care-dependent, non-endocrine critical illness.

Alterations within several of the endocrine axes briefly touched upon in the overview chapter are then further discussed in detail in the following chapters: critical illness induced alterations within the growth hormone axis, the thyroid axis and the pituitary adrenal axis, changes in catecholamines, glucose control and salt and water metabolism.

Endocrinology and Metabolism Clinics of North America

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Practical management of glucose intolerance is discussed from nonpharmacologic techniques to various pharmacologic therapies. Current prescribing guidelines for oral agents are included, along with information on the various insulin regimens. Guidance is provided on analyzing home glucose monitoring results.

Diagnosis and Management of Type 2 Diabetes, 7E

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