Medical Textbook Detail:

* Publisher: Not Avail
* Number Of Pages: 252
* Publication Date: 2008-01
* ISBN-10 / ASIN: 1904392849
* ISBN-13 / EAN: 9781904392842
* Binding: Paperback

Medical Textbook Description:
This new volume brings together the current thinking in both investigation and management of the cancer patient. It presents a comprehensive caseload as seen by the oncologist. These are common yet challenging real-life patient scenarios, which the authors resolve by drawing on the latest published literature. Each case begins with a few practical questions to stimulate the reader. This is followed by clinical presentation and the reader is led through the logical work-up of a case to reach a diagnosis.

Contents:
* Basic Biostatistics
* Pharmacology
* Principles of Chemotherapy
* Principles of Radiation Oncology
* Critical Care

Medical Book Details:

Description:

Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk.

The Molecular Genetics in Lung Cancer describes how the new techniques, methods and approaches of molecular genetics have been used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumor classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumors arise and how they progress to malignancy.

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Description:

In this issue of the Thoracic Surgery Clinics, the authors focus on many points of discussion in present and evolving diagnostic and therapeutic paradigms for stage I Non-Small Cell Lung Cancer. We begin with discussions of the role of roentgenographic surveillance of patients at increased risk for development of Non-Small Cell Lung Cancer. Henschke provides us with compelling arguments for the use of “fast”, low-dose CT screening for middle-aged persons with significant smoking history and some evidence of Chronic Obstructive Pulmonary Disease ( COPD ). Her analysis suggests that such screening is cost-effective in detecting and treating lung cancer at an early, curative stage. She compares the effectiveness of such lung cancer surveillance to that of routine mammography in the detection of early-stage breast cancer. Advances in percutaneous and transbronchial image-guided diagnostics are reviewed by Yankelevitz and Ernst. The emerging role of molecular biologic staging as a means of detecting a higher risk of recurrence among patients with stage I Non-Small Cell Lung Cancer by the classic TNM staging system is described by Doctor Harpole. Roth and Luketich give us intriguing insight into the growing enthusiasm for and the potential emerging role of hyperfractionated radiotherapy and radiofrequency ablation techniques for the small peripheral Non-Small Cell Lung Cancer. Although most thoracic surgeons continue to disqualify these approaches as reasonable front-line therapeutic approaches to resectable Non-Small Cell Lung Cancer, other competitive medical disciplines are promoting these interventions as both minimally invasive and effective. The “can do” individualistic spirit of thoracic surgeons is one of our strongest attributes. Thoracic surgeons may choose to ignore these efforts, similar to the tale of the elephant who sticks his trunk under the circus tent. Rather than despair and cry out, “Who is John Galt?”, thoracic surgeons can begin to engage themselves in these percutaneous and radiotherapy techniques. Thoracic surgeons should become fully acquainted with these approaches and establish these modalities as another arrow in their quiver for the treatment of stage I Non-Small Cell Lung Cancer. Neurosurgeons, vascular surgeons, and urologists have faced similar circumstances over the last two decades, and they have positioned themselves to maintain their leadership position in the management of their particular areas of clinical interest. Just as we profess that our surgical approach to esophageal disease should not be governed by the thin muscular slip known as the “diaphragm”, our active, involved approach to curable lung cancer should not be restricted by the presence or absence of a radiation exposure badge. The utility of sublobar resection for the management of small peripheral Non-Small Cell Lung Cancers is argued by Pettiford and colleagues. This sublobar resection approach is also described by Yoshida in his appraisal of the management of the peripheral pulmonary “ground glass” opacity. Local recurrence being a primary failure of these sublobar resection approaches has led us to explore the value of adjuvant radiation therapy following sublobar resection. Fernando nicely describes the possible role of intraoperative brachytherapy in reducing this local recurrence event. Maddaus provides us with a contrary point of view in favor of lobectomy for stage I lung cancer, and Rendina gives us insight into the importance of accurate lymph node staging during the course of anatomic lung resection. Rendina also provides further support for the use of mediastinal lymphadenectomy following resection of stage I Non-Small Cell Lung Cancer. Thoracoscopic approaches to lobectomy and their merits are described by McKenna and Yim. Walker elaborates on his work in pro?ling the differences in immunologic suppression between open and thoracoscopic approaches to lobectomy. The potential role of adjuvant chemotherapy following complete resection of stage I Non-Small Cell Lung Cancer is provided by Vallieres. Although medical science, like most other sciences, is “empirical” by nature, d’Amato argues that a logical approach to this empiric knowledge be used when suggesting systemic therapy following R0 resection of stage I non–small cell lung cancer.

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Description:
Textbook of Lung Cancer, 2nd edition, published in association with the European Society of Medical Oncology, is a comprehensive and multidisciplinary text, which examines all aspects of this disease, with contributions from a multinational team of authors on etiology, epidemiology, molecular biology, pathology, smoking, detection and management, clinical features, staging and prognostic factors, surgery, radiotherapy and chemotherapy. It provides essential information and guidance for specialist trainees in oncology, and for the many physicians and specialists involved in the field of lung cancer.

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Description:

Essential reading for both medical students and academics in the fields of ophthalmology, neurology and oncology, this is the first textbook to cover the subject of primary intraocular lymphoma. The book serves to educate ophthalmologists, neurologists and oncologists on a disease process that is often difficult to diagnose. To help readers recognize the malignancy, a presentation of common and less frequently occurring clinical manifestations of the disease is given. The book provides ophthalmologists the guidelines on current diagnostic and therapeutic modalities as well as the historical background of primary intraocular lymphoma.

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Product Detail:
* Publisher: Informa HealthCare
* Number Of Pages: 600
* Publication Date: 2008-11-24
* ISBN-10 / ASIN: 0849340543
* ISBN-13 / EAN: 9780849340543

 

Product Description:
The management of tumors in and adjacent to the skullbase is challenging given the complex and critically important anatomy of the region and the wide diversity of tumor pathologies that may be encountered.

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